Most countries have active vaccination programmes for children aged tw
o months and older. It is likely that many children presenting for med
ical procedures which require general anaesthesia have been vaccinated
recently. Although there is no evidence suggesting increased risks as
sociated with anaesthetizing recently vaccinated children there are ma
ny theoretical reasons why this situation needs critical assessment an
d review. After vaccination there is local swelling and pain at the si
te of the injection and the most common side effects seen are fever, m
alaise, headache, rash and myalgia which may last from one day to thre
e weeks. Anaesthesia, stress and trauma are known to suppress the immu
ne system. It is suggested that if possible, children should not be su
bjected to anaesthesia for elective procedures within two to three wee
ks after vaccination. Urgent procedures should be managed according to
anaesthetic principles which will minimize the effect of anaesthesia
on the physiological system affected by the immunization process at th
e time. Paediatric anaesthesia risk management programmes should inclu
de vaccination data to enable the risks of anaesthesia in recently vac
cinated children to be analysed.