A case of giant phaeochromocytoma occurring in a 47-year-old man with
no signs or symptoms of catecholamine secretion is reported. Abdominal
ultrasound scanning, chest X-ray, computed tomography and magnetic re
sonance imaging were preoperatively performed. The patient was operate
d through a thoracoabdominal incision and section of the left hemidiap
hragm. The giant retroperitoneal mass was en-bloc resected together wi
th the left adrenal gland. Macroscopic sectioning showed a smoothly ro
unded 29 x 21 x 12 cm tumour attached to a normal left adrenal gland,
weighing 4050 gr. The huge size of the neoplasm, the several areas of
necrosis, the size and monomorphic appearance of the cells, and the la
rge number of mitotic figures afforded a diagnosis of malignant phaeoc
hromocytoma.