Jr. Mcclellan et al., PATTERNS OF USE AND CLINICAL UTILITY OF EXERCISE TL-201 SINGLE-PHOTONEMISSION-COMPUTED TOMOGRAPHY IN A COMMUNITY-HOSPITAL, Cardiology, 87(2), 1996, pp. 134-140
Single photon emission computed tomographic (SPECT) imaging with thall
ium-201 was evaluated in 492 consecutive, unselected patients to ascer
tain the patterns of use and additive value to the exercise electrocar
diogram in the diagnosis of myocardial ischemia in a community hospita
l setting, Myocardial perfusion images were interpreted by a single ob
server employing visual and confirmatory quantitative analysis. The ma
jority of patients (69%) were studied to evaluate the functional conse
quences of known coronary artery disease and not primarily to aid in d
iagnosis, Relationships among exercise electrocardiograms, SPECT infor
mation and coronary angiography were analyzed in 303 patients. The sen
sitivity was 92% and improved to 96% when multivessel disease was pres
ent, Overall, the positive predictive value of tomographic imaging in
the detection of coronary disease was 94%, These findings demonstrate
the changing pattern of use of myocardial perfusion imaging and confir
m the value and applicability of this technique in routine clinical pr
actice.