NOVEL TETRANUCLEOTIDE REPEAT POLYMORPHISM IN THE HUMAN ADENOSINE-DEAMINASE GENE - INTERETHNIC COMPARISON OF 3 MAJOR HUMAN GROUPS

Authors
SCOZZARI R CRUCIANI F SANTOLAMAZZA P PARRA E SELLITTO D MODIANO D MELONI G CAI WW MORAL P
Citation
R. Scozzari et al., NOVEL TETRANUCLEOTIDE REPEAT POLYMORPHISM IN THE HUMAN ADENOSINE-DEAMINASE GENE - INTERETHNIC COMPARISON OF 3 MAJOR HUMAN GROUPS, Human biology, 68(2), 1996, pp. 315-320
Citations number
12
Categorie Soggetti
Genetics & Heredity",Biology
Journal title
Human biology → ACNP
ISSN journal
00187143
Volume
68
Issue
2
Year of publication
1996
Pages
315 - 320
Database
ISI
SICI code
0018-7143(1996)68:2<315:NTRPIT>2.0.ZU;2-#
Abstract
A new tetranucleotide repeat polymorphism was revealed at the human ad enosine deaminase (ADA) locus by using the polymerase chain reaction a nd denaturing polyacrylamide gel electrophoresis. Allele frequencies w ere estimated in seven populations from three major ethnic groups. Het erozygosity values were calculated and found to differ significantly b etween Africans and non-Africans.