Tuberculosis was a major health problem in Norway in the first part of
the century, but since the thirties there has been a dramatic and ste
ady decline in incidence. However, for various reasons, including tube
rculosis in foreign-born residents, there has been no definite decreas
e in notified cases during the last decade. The emergence of drug resi
stant strains of M. tuberculosis has up to now not been a problem of a
ny significance. Leprosy reached its peak incidence in the 19th centur
y. Nowadays the few imported cases seen, on average less than one a ye
ar, may represent a diagnostic challenge, Therapeutically, we have ado
pted a modification of the multidrug regime introduced and recommended
by WHO a decade ago. Available figures indicate that diseases due to
other mycobacteria, so-called atypical mycobacteria, may be an increas
ing problem. A small part of the observed increase is due to infection
s with Mycobacterium avium-intracellulare complex in AIDS patients.