We describe the clinical and histopathological findings of a conjuncti
val papilloma due to papillomavirus. The therapeutic method applied wa
s excision plus cryotherapy. These lesions are known to recur, and pap
illomavirus DNA sequences are present in several cases of conjunctival
dysplasia and carcinoma. Using biological molecular methods (in situ
hybridization, Southern blot hybridization, and particularly polymeras
e chain reaction), more than 60 Human Papillomavirus have currently be
en reported. This new detection techniques improve the possibility of
findings HPV infection, and increase the interest for this virus extre
mely widely distributed in man.