GENETICS OF COXSACKIEVIRUS B3 CARDIOVIRULENCE

Authors
TRACY S TU Z CHAPMAN N HUFNAGEL G
Citation
S. Tracy et al., GENETICS OF COXSACKIEVIRUS B3 CARDIOVIRULENCE, European heart journal, 16, 1995, pp. 15-17
Citations number
19
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
European heart journal → ACNP
ISSN journal
0195668X
Volume
16
Year of publication
1995
Supplement
O
Pages
15 - 17
Database
ISI
SICI code
0195-668X(1995)16:<15:GOCBC>2.0.ZU;2-Z
Abstract
The human enteroviruses, especially the coxsackie B viruses, have been established as aetiologic agents of human inflammatory heart disease, a condition which may lend to dilated cardiomyopathy and heart failur e. It is clear from murine models of coxsackievirus B3-induced inflamm atory heart disease that not all strains of the virus are cardiovirule nt (able to cause disease). Here, we present preliminary data mapping the sire in a coxsackievirus B3 genome which determines a cardiovirule nt phenotype.