CELLULAR IMMUNE-MECHANISMS IN MYOSIN-INDUCED MYOCARDITIS

Authors
PUMMERER C GRASSL G NEU N
Citation
C. Pummerer et al., CELLULAR IMMUNE-MECHANISMS IN MYOSIN-INDUCED MYOCARDITIS, European heart journal, 16, 1995, pp. 71-74
Citations number
21
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
European heart journal → ACNP
ISSN journal
0195668X
Volume
16
Year of publication
1995
Supplement
O
Pages
71 - 74
Database
ISI
SICI code
0195-668X(1995)16:<71:CIIMM>2.0.ZU;2-0
Abstract
Cardiac myosin-induced myocarditis proved to be a valuable virus-free murine model with which to investigate autoimmunological mechanisms in inflammatory heart disease. The disease was shown to be T cell-mediat ed. In this contribution the functional role of CD4 and CD8 molecules and the conditions that are required to make the cardiac tissue suscep tible to an autoimmune attack are discussed.