R. Loire et P. Boissonnat, CARDIAC RETRANSPLANTATION (42 PROCEDURES IN 38 PATIENTS) - INDICATIONS AND OUTCOME, Archives des maladies du coeur et des vaisseaux, 89(2), 1996, pp. 229-234
In order to determine the results of cardiac retransplantation 38 case
s were reviewed (42 transplantations; 4 patients underwent 3 transplan
tations). Clinical indications included acute rejection and infection
before and after retransplantation : the explanted heart was sent for
anatomopathological study. The indications were dominated by coronary
artery disease of the graft (26 cases) with an average of 45.3 months
between the two transplantations and a long-term survival comparable t
o that of primotransplantation. Conversely, in the other indications o
f retransplantation,the delay was much shorter (less than 12 days in h
alf the cases) and the results were poor (9 deaths out of 12 cases). T
herefore, coronary disease of the graft would seem to be the only just
ified indication for retransplantation at it associates stable haemody
namic conditions and therapeutic impregnation comparable to the primot
ransplantation.