We present three cases of abdominal and abdomino-thoracic extra-lobar
pulmonary sequestrations detected by antenatal ultrasound (US) over a
12-month period. In addition, we briefly refer to a case previously de
scribed. A cystic mass was demonstrated in the left upper abdomen of t
he fetus in all four cases, with two extending into the thorax. The di
agnosis was confirmed postnatally by fine-needle biopsy and later exci
sion of the mass. In all four cases the lesion did not interfere with
the pregnancy, and only one child demonstrated transient effects of mi
ld pulmonary hypoplasia. Review of the antenatal scans showed that in
each case the sequestration did not appear to grow during the pregnanc
y, with a relative decrease in size. Extra-lobar sequestration should
always be considered in the differential diagnosis of an abdominal mas
s diagnosed on antenatal US, especially if cystic and extending from t
he abdomen through the diaphragm into the mediastinum. Although abdomi
nal sequestrations are rare in comparison to thoracic lesions at postn
atal diagnosis, they represent 21 of the 40 published series of pulmon
ary sequestrations diagnosed on antenatal US.