Choledochal cysts are now being diagnosed before birth on routine mate
rnal sonography (US). There is no report in the literature outlining t
he management of newborns with choledochal cysts, many of whom are asy
mptomatic. Our study details the diagnosis, treatment and outcome of s
ix such children, four girls and two boys. Five had antenatal US revea
ling cystic abdominal masses. One had intermittent vomiting and US sug
gested a choledochal cyst. Four of six had normal serum bilirubin leve
ls; two had elevations. In five babies the choledochal cyst was correc
tly diagnosed from the preoperative studies; in one the preoperative d
iagnosis was an ovarian cyst. The children underwent an operation at a
n average of 6 weeks of age (range 5 days to 17 weeks). At exploration
, cholangiography showed Alonso-Lej type I cysts in all cases. Treatme
nt consisted of resection of the cyst with Roux-en-Y choledochojejunos
tomy in five and with a valved jejunal choledochoduodenal conduit in o
ne. In no case was the dissection of the choledochal cyst off the port
al vein and hepatic artery difficult. There were no intra- or early po
stoperative complications. Mean hospital stay was 8 days (range 5 to 9
days). Presently, all 6 patients have normal bilirubin levels at an a
verage length of follow-up of 35 months (range 16 to 70 months) after
operation. We conclude that operative treatment of choledochal cysts i
n early infancy, even in asymptomatic children, is safe and effective
and may prevent serious complications later in life.