Despite the excellent results achieved with the endocardial resection
procedure in the management of patients with life-threatening ventricu
lar tachycardia. Most surgical electrophysiology teams have experience
d a decline in the number of direct operations performed for life-thre
atening ventricular tachycardia. This is probably due to the widesprea
d use of thrombolytic therapy during the acute phase of infarct format
ion. But also to the advent of implantable cardioverter-defibrillators
that are increasingly sophisticated, easy to use and effective. Their
increased use over the past few years is related to the belief that d
irect operations for the eradication of ventricular tachycardia foci b
ear a high operative mortality rate. However, today the operative mort
ality is less than 5%, and long term survival is up to 85% at 5 years
with an extremely low incidence of ventricular tachycardia recurrence
and sudden death. We report the results obtained in our first 100 pati
ents in whom ventricular tachycardia surgical ablation was guided by c
omputerized mapping of both the endocardium and epicardium. A particul
ar type of ventricular tachycardia activation pattern was found to be
associated with a higher rate of electrical failure due to a deep sept
al substratum. Appropriate management of this condition may further de
crease the rate of ventricular tachycardia reinducibility and long ter
m return of ventricular tachycardia to a level yet unachieved by any o
ther therapeutic modality. The results of catheter ablation are promis
ing, but access to intramural substrates remains unresolved. In patien
ts with sustained monomorphic ventricular tachycardia associated with
a discrete akinetic area of the left ventricle, surgery offered as a l
ast resort is less likely to produce favourable results and the decisi
on of its use should therefore be taken early before unjustified drug
trials go on.