This single-group prospective cohort study was conducted to define the
efficacy and safety of single-portal endoscopic carpal tunnel release
using the redesigned carpal tunnel release system (3M Healthcare, St
Paul, MN). Eighty-six procedures in 69 patients were evaluated by obje
ctive motor/sensory testing and clinical outcome questionnaire at 10 d
ays, and 6 and 10 weeks postoperatively. All cases were performed by t
he same surgeon using a similar local anesthetic technique. The subjec
tive symptoms of carpal tunnel syndrome, including paresthesia, numbne
ss, and pain, demonstrated substantial improvement by 10 days postoper
atively, and less than 2% of the subjects remained symptomatic by 10 w
eeks. The percentage of patients with normal, static, two-point discri
mination in the median nerve distribution, demonstrated significant im
provement by 6 weeks postoperatively. Preoperative grip and three-poin
t pinch strength were regained by 6 weeks postoperatively, while later
al pinch demonstrated substantial improvement in the same time period.
Workers' compensation cases required a significantly longer time to r
eturn to work (mean, 40.8 days) than nonworkers' compensation cases (m
ean, 22.2 days). No difference, however, was demonstrated between work
ers' compensation and nonworkers' compensation cases with respect to t
he time of return to activities of daily living(mean, 13.5 days). ther
e were no major neurovascular injuries incurred during the performance
of the study. The most important complications included one mild refl
ex sympathetic dystrophy, three transient digital neuropraxias, and on
e superficial wound infection. In conclusion, the performance of singl
e-portal endoscopic carpal tunnel release using the redesigned Agee ca
rpal tunnel release system is both a safe and efficacious procedure.