H. Vonbaeyer et al., LDL-APHERESIS IN COMBINATION WITH TREATME NT OF 7 FAMILIAL HYPERCHOLESTEROLEMIA - METHODS AND RESULTS, Die medizinische Welt, 47(2), 1996, pp. 74-78
Consideration of own experience and literature leads to the following
conclusions: LDL-apheresis in combination with high dose drug therapy
and low cholesterol diet is indicated in cases of severe familial hype
rcholesterolemia. The currently available procedures have almost equal
efficacy. Pros and cons are minor. The choice can only be based on pr
actical reasons and costs. The therapeutical success is the prevention
of myocardial infarction. Redardation of coronary heart disease (CHD)
this combined therapy is possible. The accelerated CHD of patients wi
th severe familial hypercholesterolemia changes to the slowly progress
ing form that occurs if risk factors are controlled.