EVALUATION OF IOHEXOL AS A MARKER FOR THE CLINICAL MEASUREMENT OF GLOMERULAR-FILTRATION RATE IN DOGS

Authors
GLEADHILL A MICHELL AR
Citation
A. Gleadhill et Ar. Michell, EVALUATION OF IOHEXOL AS A MARKER FOR THE CLINICAL MEASUREMENT OF GLOMERULAR-FILTRATION RATE IN DOGS, Research in Veterinary Science, 60(2), 1996, pp. 117-121
Citations number
26
Categorie Soggetti
Veterinary Sciences
Journal title
Research in Veterinary Science → ACNP
ISSN journal
00345288
Volume
60
Issue
2
Year of publication
1996
Pages
117 - 121
Database
ISI
SICI code
0034-5288(1996)60:2<117:EOIAAM>2.0.ZU;2-1
Abstract
The contrast medium iohexol can be used as a marker for the measuremen t of glomerular filtration rate. It has the advantages of sample stabi lity and the availability of a simple, automated (though expensive) an alyser. The clearance of iohexol was compared with the clearance of Tc -DTPA in 24 dogs with known or suspected renal impairment. The results were comparable but fractionally lower with iohexol. The correction f actors developed for human beings were found to be satisfactory in the dogs, thus validating the software routines used in the automated ana lyser with the canine samples.