Dpc. Mcgee et al., NOVEL NUCLEOSIDES VIA INTRAMOLECULAR FUNCTIONALIZATION OF 2,2'-ANHYDROURIDINE DERIVATIVES, Tetrahedron letters, 37(12), 1996, pp. 1995-1998
The generation of novel ribonucleoside analogues derived from 2,2'-anh
ydrouridines by a 3'-hydroxyl directed intramolecular nucleophilic sub
stitution of the 2'-position is described. The methodology allows for
the efficient, regio- and stereoselective elaboration of the 2'-positi
on, often under exceptionally mild reaction conditions.