Objective: Coincident with a change in the physician staff in our pedi
atric intensive care unit (PICU), the frequency and duration of invasi
ve monitoring were decreased. We examined the impact of this change on
outcomes, complications, and hospital charges in infants admitted to
the PICU with respiratory syncytial virus (RSV) infection. Study desig
n: We reviewed medical records of all children less than 1 year of age
who were admitted to the PICU from January 1989 to July 1993 with con
firmed RSV infection, Patient characteristics, therapeutic interventio
ns, outcomes, and hospital charges were extracted and compared. Result
s: Seventy-eight patients were identified, 38 admitted from January 19
89 through July 1991 (group 1) and 40 from July 1991 through July 1993
(group 2), The groups were well matched in age, preexisting disease,
and cardiorespiratory status on admission, Group 1 had significantly g
reater use of invasive monitoring, pharmacologic paralysis, inotropes,
blood products, antibiotics, and parenteral nutrition, Outcomes were
not different, but group 1 patients had significantly longer stays, mo
re complications, and higher hospital charges. Conclusions: Routine us
e of invasive monitoring of PICU patients with RSV disease was associa
ted with increased laboratory testing, overtreatment, and significant
increases in costs and morbidity without improvement in outcome.