M. Summar et al., EFFECTIVE HEMODIALYSIS AND HEMOFILTRATION DRIVEN BY AN EXTRACORPOREALMEMBRANE-OXYGENATION PUMP IN INFANTS WITH HYPERAMMONEMIA, The Journal of pediatrics, 128(3), 1996, pp. 379-382
Two infants with urea cycle disorders had life-threatening hyperammone
mia within the first 5 days of life, Both patients were small for date
s, poorly oxygenated, and hemodynamically unstable, We employed a comb
ination of extracorporeal oxygenation and hemodialysis to provide high
-flow filtration in a controlled system to rapidly detoxify both patie
nts.