We report the first Israeli pediatric case of Kikuchi's disease in a 1
0-year-old male. He was hospitalized for evaluation of migrating arthr
algia and fever. Axillary adenopathy was the main physical finding. A
biopsy showed a histiocytic necrotizing lymphadenitis. Diagnosis, ther
apeutic options and the clinical significance of Kikuchi's disease are
discussed. Kikuchi's disease should be considered in the differential
diagnosis of fever of unknown origin in children, even in the absence
of cervical adenopathy. A long follow-up is advised because of possib
le links with systemic lupus erythematosus and to detect eventual late
recurrences.