SARCOIDOSIS AFTER INTERFERON THERAPY FOR CHRONIC ACTIVE HEPATITIS-C

Authors
TERAGAWA H HONDO T TAKAHASHI K WATANABE H OHE H HATTORI N WATANABE Y AMANO H HINO F OHBAYASHI M URUSHIHARA T YONEHARA S
Citation
H. Teragawa et al., SARCOIDOSIS AFTER INTERFERON THERAPY FOR CHRONIC ACTIVE HEPATITIS-C, Internal medicine, 35(1), 1996, pp. 19-23
Citations number
20
Categorie Soggetti
Medicine, General & Internal
Journal title
Internal medicine → ACNP
ISSN journal
09182918
Volume
35
Issue
1
Year of publication
1996
Pages
19 - 23
Database
ISI
SICI code
0918-2918(1996)35:1<19:SAITFC>2.0.ZU;2-U
Abstract
Sarcoidosis is characterized by multisystemic granulomatous lesions of unknown etiology. A 62-year-old woman developed sarcoidosis after tre atment with alpha-2a interferon (IFN) for 24 weeks (total dose: 522 mi llion units) for chronic hepatitis C. She developed complete atriovent ricular block and multiple noncaseating granulomatous lesions in the l ung. IFN therapy, which may disturb cellular immune activation in some patients, may have contributed to the onset and progression of sarcoi dosis.