A. Ekelund et al., IS TRANSCRANIAL DOPPLER SONOGRAPHY USEFUL IN DETECTING LATE CEREBRAL-ISCHEMIA AFTER ANEURYSMAL SUBARACHNOID HEMORRHAGE, British journal of neurosurgery, 10(1), 1996, pp. 19-25
Transcranial Doppler (TCD) examination was performed in 109 patients w
ith aneurysmal subarachnoid haemorrhage. Fifty-seven demonstrated flow
velocities exceeding 120 cm/s in the middle cerebral artery. Of these
, 23 developed delayed ischaemic deficit (DID). Mean flow velocity in
this group was 170, SD 12.8 cm/s, in comparison with 155, SD 11.2 cm/s
in the 34 patients without late signs of cerebral ischaemia. This dif
ference is significant (p = 0.0269). :In the 34 patients without DID,
but TCD > 120 cm/s, 17 received anti-ischaemic therapy based on TCD va
lues only, while 17 were given no additional treatment. The mean TCD v
alues and the neurological outcome in the two groups were similar. A r
apid increase in flow velocities of 50 cm/s or more during a 24-h peri
od seemed to be a strong predictor of symptomatic vasospasm as seven o
ut of 12 patients developed DID, five with permanent neurological sequ
elae. The study confirms results from other centres, that a strict cor
relation between high TCD flow velocities and the occurrence of DID do
es not exist.