T. Mathiesen et Ak. Lefvert, CEREBROSPINAL-FLUID AND BLOOD LYMPHOCYTE SUBPOPULATIONS FOLLOWING SUBARACHNOID HEMORRHAGE, British journal of neurosurgery, 10(1), 1996, pp. 89-92
Lymphocyte subpopulations from 10 patients who had had a subarachnoid
haemorrhage were analysed. In CSF, an increase of CD3 cells was found
in mio of ten, CD4 in one of ten, CD8 in three of ten, and CD19 in thr
ee of ten patients. Three patients with delayed ischaemic deficit (DID
) showed a statistically significant increase of intrathecal suppresso
r/cytotoxic/NK-cells. The cellular inflammation had been modulated wit
hin the CNS indicating a pathogenic role in the biochemical cascades f
ollowing SAH.