THE NONCODING AND SURFACE ENVELOPE CODING SEQUENCES OF MYELOBLASTOSIS-ASSOCIATED VIRUS ARE RESPECTIVELY RESPONSIBLE FOR NEPHROBLASTOMA DEVELOPMENT AND RENAL HYPERPLASIA

Authors
JOLIOT V KHELIFI C WYERS M DAMBRINE G LASSERRE F LEMERCIER P PERBAL B
Citation
V. Joliot et al., THE NONCODING AND SURFACE ENVELOPE CODING SEQUENCES OF MYELOBLASTOSIS-ASSOCIATED VIRUS ARE RESPECTIVELY RESPONSIBLE FOR NEPHROBLASTOMA DEVELOPMENT AND RENAL HYPERPLASIA, Journal of virology, 70(4), 1996, pp. 2576-2580
Citations number
27
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
70
Issue
4
Year of publication
1996
Pages
2576 - 2580
Database
ISI
SICI code
0022-538X(1996)70:4<2576:TNASEC>2.0.ZU;2-Y
Abstract
The use of chimeric viruses allowed us to establish that myeloblastosi s-associated, virus long terminal repeat sequences are necessary and s ufficient for induction of nephroblastoma in chickens and that the bla stemal hyperplasia induced by env SU is not a prerequisite for tumor d evelopment but rather constitutes a predisposing stage.