Objectives. Wilms' tumor is the most common solid abdominal tumor of c
hildhood. Wilms' tumor is extremely rare in the neonate, with less the
n 20 well-documented cases. No bilateral lesions in neonates have been
described in the literature. Methods. We report on a neonate who pres
ented with synchronous bilateral Wilms' tumors. Results. Child underwe
nt bilateral partial nephrectomy, followed by standard chemotherapy, a
nd is now well 2 years after completion of the therapy without any evi
dence for recurrent disease. Conclusions. Wilms' tumor should be inclu
ded in the differential diagnosis of the solid renal mass in the neona
te.