A 65-year old male Saudi patient presented with rapidly progressive qu
adriparesis. Lower cervical myelopathy was associated with radiologica
l features of bone destruction, inflammatory disease of the spine and
a paravertebral mass. Although tuberculosis and brucellosis are more c
ommonly responsible for this clinical picture in our practice, Staphyl
ococcus aureus was isolated from tissue recovered at surgery. He has b
een followed up for 12 months and has made an almost complete recovery
after surgical decompression of spinal cord and a 2-month course of i
ntravenous flucloxacillin. This case underscores the need for tissue d
iagnosis in patients presenting with inflammatory paravertebral swelli
ngs even in areas endemic for tuberculosis and brucellosis.