Sw. Huang et Jw. Kimbrough, EFFECT OF AIR CLEANERS ON MOLD COUNT IN THE AIR AND ON THE SYMPTOMS OF PERENNIAL RHINITIS, Pediatric asthma, allergy & immunology, 9(4), 1995, pp. 205-211
Seventy-five children (ages 4 to 14 years) with perennial rhinitis cau
sed by mold allergy (36 had asthma) were enrolled in an air-cleaner st
udy for 2 years. Symptom scores prior to the study were compared with
scores 1 and 2 years after placement of air-cleaners in the bedrooms.
Forty-two homes were surveyed for mold count in the air in summer and
winter, and the results compared with symptom changes. Improvements we
re found in quality of sleep (96 vs. 99%), sneezing (80 vs. 90%), scra
tchy throat (75 vs. 80%), night cough (75 vs. 83%), better mood in the
morning (65 vs. 80%), postnasal drip (70 vs. 77%), nasal congestion (
70 vs. 72%), night wheezing (70 vs. 83%), and sinus infection (50 vs.
55%). Parents reported a decrease in the use of both over-the-counter
(76 vs. 80%) and prescription (43 vs. 48%) drugs. When the weekly symp
tom score sheets were compared, symptom recurrence rates were found to
be clustered in the winter. These symptoms were cough (35%), nasal co
ngestion (35%), sinus infection (32%), and postnasal drip (20%). The a
verage mold counts (expressed as colony-forming-units per cubic meter
of air) in the filtered bedrooms, in the unfiltered bedrooms, and outd
oors were 310, 425, and 927 in the summer, and 689, 762, and 1213 in t
he winter, respectively. The higher mold count in the winter may expla
in the increase in symptoms during that season. We observed a signific
ant improvement in respiratory symptoms for 2 years following the inst
allation of air-cleaners in the bedrooms of 75 children with perennial
rhinitis due to mold allergy.