ACUTE LEUKEMIAS AFTER APLASTIC ANEMIAS IN CHILDHOOD

Only few reports about ALL after aplastic anaemias in childhood exist. It remains still unclear which immunophenotypes of the leukaemias mus t be expected thereafter. Here it is reported about two children with quite different immunophenotypes of the leukaemic cells. In the first one the most common type was found, the constellation of a c-ALL, wher eas in the other the precise classification was impossible at all. Mye loic and T-cell markers were present at the same time. This form of le ukaemia was not influenced therapeutically in a sufficient manner. The patient died after recovery phases of only short duration. After apla stic anaemias with fast recovery by prednisolone ALL of different cons tellation has to be expected. Therefore the antileukaemic treatment im mediately after recovery of the aplastic anaemia should be taken into consideration.