ANGIOTENSIN-CONVERTING ENZYME (ACE) GENE POLYMORPHISM IN TYPE-II DIABETIC-PATIENTS WITH INCREASED ALBUMIN EXCRETION RATE

Authors
PANAGIOTOPOULOS S SMITH TJ ALDRED GP BAKER EJ JACKLIN CJ JERUMS G
Citation
S. Panagiotopoulos et al., ANGIOTENSIN-CONVERTING ENZYME (ACE) GENE POLYMORPHISM IN TYPE-II DIABETIC-PATIENTS WITH INCREASED ALBUMIN EXCRETION RATE, Journal of diabetes and its complications, 9(4), 1995, pp. 272-276
Citations number
39
Categorie Soggetti
Endocrynology & Metabolism","Gastroenterology & Hepatology
Journal title
Journal of diabetes and its complications → ACNP
ISSN journal
10568727
Volume
9
Issue
4
Year of publication
1995
Pages
272 - 276
Database
ISI
SICI code
1056-8727(1995)9:4<272:AE(GPI>2.0.ZU;2-R
Abstract
Approximately one in three patients with diabetes is at risk of develo ping kidney disease, despite current methods of treatment, It has long been suspected that diabetic kidney disease has a genetic basis, but this has been difficult to prove. Polymorphisms of the angiotensin-con verting enzyme (ACE) gene have been shown to be related to the occurre nce of nephropathy in type I diabetic patients, This study showed that there was no association in the ACE genotype frequency and increased albumin excretion rate in type II diabetic patients.