A SEQUENCE-ANALYSIS OF THE BETA-GLUCOSIDASE SUBFAMILY-B

This computational study is a summary of structural properties of the beta-glucosidase subfamily B. Computations were carried out using GCG package programs. All sequences used in this analysis were taken from the protein data bank. The multialignment and the phylogenetic tree of the beta-glucosidase subfamily B are shown. The conserved patterns: D GP, GRNFE, DPYL, KHF, SDW GLD, VLLKN in the N-terminal region and FGYG LSY in the C-terminal part should be pointed out. C-terminal parts of the Butyrivibrio fibrisolvens and Ruminococcus albus beta-glucosidase sequences can be aligned to the N-terminal region of the other members of the subfamily. A crossed homology model in sub-family B beta-gluco sidases is described.