SERUM ROTAVIRUS NEUTRALIZING-ANTIBODY TITERS COMPARED BY PLAQUE REDUCTION AND ENZYME-LINKED IMMUNOSORBENT ASSAY-BASED NEUTRALIZATION ASSAYS

Authors
WARD RL KAPIKIAN AZ GOLDBERG KM KNOWLTON DR WATSON IW RAPPAPORT R
Citation
Rl. Ward et al., SERUM ROTAVIRUS NEUTRALIZING-ANTIBODY TITERS COMPARED BY PLAQUE REDUCTION AND ENZYME-LINKED IMMUNOSORBENT ASSAY-BASED NEUTRALIZATION ASSAYS, Journal of clinical microbiology, 34(4), 1996, pp. 983-985
Citations number
19
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
34
Issue
4
Year of publication
1996
Pages
983 - 985
Database
ISI
SICI code
0095-1137(1996)34:4<983:SRNTCB>2.0.ZU;2-J
Abstract
Comparisons in rotavirus neutralizing-antibody responses were made wit h sera collected from vaccinated infants. The methods were a plaque re duction assay and a new enzyme-linked immunosorbent assay-based neutra lization assay. Agreement of 94% was found in detecting at least fourf old seroresponses, and correlation coefficients between titers obtaine d by the two methods showed excellent agreement, indicating that eithe r could be used reliably.