L. Exmelin et al., MOLECULAR STUDY OF NOSOCOMIAL NOCARDIOSIS OUTBREAK INVOLVING HEART-TRANSPLANT RECIPIENTS, Journal of clinical microbiology, 34(4), 1996, pp. 1014-1016
Randomly amplified polymorphic DNA analysis and rRNA gene restriction
patterns (ribotyping) were compared as methods of investigating a noso
comial outbreak of nocardiosis involving three heart transplant recipi
ents. No clear distinctions between three clinically related isolates
and four unrelated strains were obtained by ribotyping. On the contrar
y, randomly amplified polymorphic DNA analysis with two selected prime
rs, primers 2650 and DKU49, showed one pattern for the three related i
solates and four patterns for the unrelated strains.