EXTRACTS OF GINKGO-BILOBA LEAVES INHIBIT MONOAMINE-OXIDASE

Authors
WHITE HL SCATES PW COOPER BR
Citation
Hl. White et al., EXTRACTS OF GINKGO-BILOBA LEAVES INHIBIT MONOAMINE-OXIDASE, Life sciences, 58(16), 1996, pp. 1315-1321
Citations number
17
Categorie Soggetti
Biology,"Medicine, Research & Experimental","Pharmacology & Pharmacy
Journal title
Life sciences → ACNP
ISSN journal
00243205
Volume
58
Issue
16
Year of publication
1996
Pages
1315 - 1321
Database
ISI
SICI code
0024-3205(1996)58:16<1315:EOGLIM>2.0.ZU;2-6
Abstract
Extracts of Ginkgo biloba leaves produce reversible inhibition of rat brain monoamine oxidase (MAO). Both MAO-A and -B types were inhibited to a similar extent. The MAO inhibitory compound(s) were present in dr ied or fresh Ginkgo biloba leaves as well as in commercially available capsules of Ginkgo biloba and appear to be heat stable with relativel y low molecular weight. MAO inhibition by Ginkgo biloba may be a mecha nism underlying reported anti-stress and anxiolytic activities of this natural product.