EXTENSIVE NECROTIZING LIVEDO-RETICULARIS IN A PATIENT WITH CHRONIC-RENAL-FAILURE, HYPERPARATHYROIDISM AND COAGULATION DISORDER - REGRESSIONAFTER SUBTOTAL PARATHYROIDECTOMY

Necrotizing livedo reticularis is an infrequent, life-threatening comp lication,of chronic renal failure. Since Selye's studies in 1962, calc iphylaxis, i.e. acute calcium deposition in tissue, is considered the main pathomechanism, especially because hyperparathyroidism are very f requently present. However, other etiological and/or triggering factor s, such as coagulation disorders, direct cellular toxicity of parathor mone or calcium on endothelium, might be involved, acting perhaps in a cumulative way. We report a case with a circulating anticoagulant whi ch supports this hypothesis.