Fever is common in the solid organ transplant patient and may be produ
ced by a variety of processes. The approach to the febrile transplant
patient must include an extensive search for infection, which may be a
ided by considering the organ transplanted, time after transplantation
, and the patient's immunosuppressed state. In addition, a number of n
oninfectious causes of fever exist in this population, including allog
raft rejection, drug fever, and thromboembolic disease. A review of th
e pathogens commonly noted in posttransplant patients is presented, em
phasizing risk factors for disease, typical time of presentation, and
particular organ groups affected. In addition, the authors review the
noninfectious causes of fever in the solid organ transplant patient.