Some cyclization and cyclocondensation reactions of 1-(5-nitro-3-furoy
l)-3-(4-R-phenyl)thioureas 1a-1e (R = H, CH3, N(C2H5)(2), Br, CN) were
conducted. 6-R-2-(5-Nitro-3-furoylamino)benzothiazoles 2a-2c (R = H,
CH3, Br) were obtained by bromine-induced cyclization of the correspon
ding thioureas. Reacted with bromoacetone and omega-bromoacetophenone,
respectively, the derivatives 1a-1e gave ylimino)-3-(5-nitro-3-furoyl
)-4-R(1)-4-thiazolines 3a-3e (R = H, CH3, N(C2H5)(2), Br, CN; R(1) = C
H3) and 3f-3j (R = H, CH3, N(C2H5)(2), Br, CN; R(1) = C6H5), respectiv
ely. The structure of the compounds synthesized was confirmed by IR, U
V, H-1 NMR and MS data.