EFFECTS OF AEROBIC AND ANAEROBIC PHYSICAL CONDITIONING ON FIBRINOLYSIS

The effects of aerobic and anaerobic physical conditioning on fibrinol ysis were studied before and immediately after physical exercise. Mode rately active controls (group A) were compared with aerobically- (grou p B) or anaerobically-conditioned (group C) subjects, Comparison of th e resting parameters revealed that FgDP were significantly higher in g roup B as a compared to groups A and C, FbDP did not significantly dif fer between groups Band C and were significantly lower in group A, t-P A antigen and PAI antigen did not significantly differ between the thr ee groups, but t-PA activity was elevated and PAI activity and t-PA/PA I complexes were reduced in group B. Following a maximal exercise test on the treadmill both FbDP and FgDP were significantly increased in a ll groups, although values for FbDP in group B and values for FgDP in group C reached a higher level than in group A, t-PA antigen and t-PA activity were also increased in the three groups, PAI activity was sig nificantly reduced in groups A and C, t-PA/PAI complexes were signific antly enhanced in all cases, but increased to a lower degree in group B, These results indicate that both aerobic and anaerobic physical con ditioning induce activation of the fibrinolytic system.