MOLECULAR-CLONING OF MUTANT LOCI OBTAINED BY MICROINJECTION OF ONCOGENIC VIRUS-DNA INTO POLAR PLASMA OF DROSOPHILA-MELANOGASTER EARLY EMBRYOS

Authors
SOLDATOV AV NABIROCHKIN SD
Citation
Av. Soldatov et Sd. Nabirochkin, MOLECULAR-CLONING OF MUTANT LOCI OBTAINED BY MICROINJECTION OF ONCOGENIC VIRUS-DNA INTO POLAR PLASMA OF DROSOPHILA-MELANOGASTER EARLY EMBRYOS, Genetika, 32(2), 1996, pp. 192-196
Citations number
11
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
32
Issue
2
Year of publication
1996
Pages
192 - 196
Database
ISI
SICI code
0016-6758(1996)32:2<192:MOMLOB>2.0.ZU;2-Y
Abstract
Mutations w(RSV-1) and w(RSV-4) Obtained by microinjection of RSV cDNA into early embryos of Drosophila melanogaster were shown to be caused by the insertion of mobile elements jockey and B104(rov), respectivel y; partial reversion of w(RSV-1r) arose due to the deletion of a 5'-re gion of mobile element jockey and of the adjacent region of the genomi c DNA. It is concluded that genetic instability induced by oncoviral D NAs is based on the ability of these DNAs to induce transpositions of various mobile elements in the recipient genome.