Genetic disorders were studied in house mice caught from 1986 to 1993
in areas contaminated by radionuclides after the Chernobyl disaster. D
ose rates on soil surface ranged from 0.02 to 200 mR/h. Frequency of r
eciprocal translocations in spermatocytes of the mice studied was rela
tively low, but increased with dose rate. In populations, frequency of
mice heterozygous for recessive lethal mutations decreased with time
after the accident. The data obtained allow us to assume that induced
mutations may lead to elimination of germ cells and decreased viabilit
y in mice heterozygous for the mutations. These processes result in re
moving excess mutations from the population.