Rh. Anken et al., NADPH-DIAPHORASE REACTIVITY IN THE MAUTHNER CELLS OF THE SWORDTAIL FISH, XIPHOPHORUS-HELLERI, Neuroscience letters, 206(1), 1996, pp. 49-52
The presence of nicotinamide adenine dinucleotide phosphate-diaphorase
(NADPHDH) in fixed tissue was histochemically demonstrated in the Mau
thner cells of the teleost fish Xiphophorus helleri. This is the first
detection of the enzyme in these giant neurons (which are restricted
to fishes and amphibians) of a gnathostomate vertebrate. NADPHDH react
ivity in fixed tissue is thought to reflect the activity of nitric oxi
de synthase. Thus, nitric oxide, a gaseous intercellular messenger, is
probably synthesized in the Mauthner cells.