ACUTE MYELOCYTIC-LEUKEMIA ASSOCIATED WITH KAPOSIS-SARCOMA IN A PATIENT WITHOUT SERUM ANTIBODIES TO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1

We report a 35-year-old man with acute myelocytic leukaemia and Kaposi 's sarcoma, whose serum was non-reactive for antibodies to human immun odeficiency virus type-1 by enzyme-linked immunosorbent assay, Western blot and immunofluorescence. Complete remission of both the acute leu kaemia and the Kaposi's sarcoma followed treatment with mitoxantrone a nd cytosine arabinoside, We speculate that the rapid regression of the lesions of Kaposi's sarcoma might be related to mitoxantrone and to t he return to normal of his peripheral helper and suppressor T-cell cou nts.