SPONTANEOUS REGRESSION IN ANGIOCENTRIC T-CELL LYMPHOMA

An 8-year-old boy presented with a 10-week history of ulcerating lesio ns which were histologically and immunocytochemically consistent with the diagnosis of angiocentric T-cell lymphoma. The disease was limited to the skin and resolved with no chemotherapy. Angiocentric T-cell ly mphoma is commonly a disease with considerable morbidity and is often fatal. Epstein-Barr virus (EBV) could not be identified in involved ti ssue by immunostaining or by in situ hybridization. We consider whethe r the uncharacteristic absence of EBV in this case has prognostic sign ificance.