Authors
Citation
Cj. Langer et al., ACUTE ENCEPHALOPATHY ATTRIBUTED TO 5-FU, Pharmacotherapy, 16(2), 1996, pp. 311-313
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
ISSN journal
02770008
Volume
16
Issue
2
Year of publication
1996
Pages
311 - 313
Database
ISI
SICI code
0277-0008(1996)16:2<311:AEAT5>2.0.ZU;2-S
Abstract
Acute encephalopathy attributable to 5-fluorouracil (5-FU) is rare. A
patient experienced this reaction associated with a continuous 5-FU in
fusion. The etiology of the event remains uncertain, but it is general
ly reversible and does not preclude retreatment with 5-FU at reduced d
osages. Steroids and thiamine may expedite neurologic recovery.