DECREASE IN HOSPITALIZATION FOR TREATMENT OF CHILDHOOD ASTHMA WITH INCREASED USE OF ANTIINFLAMMATORY TREATMENT, DESPITE AN INCREASE IN THE PREVALENCE OF ASTHMA
G. Wennergren et al., DECREASE IN HOSPITALIZATION FOR TREATMENT OF CHILDHOOD ASTHMA WITH INCREASED USE OF ANTIINFLAMMATORY TREATMENT, DESPITE AN INCREASE IN THE PREVALENCE OF ASTHMA, Journal of allergy and clinical immunology, 97(3), 1996, pp. 742-748
Background: During the past 15 years, the prevalence of asthma in chil
dren in Sweeden has doubled. However, since, 1985, antiyinflammatory t
reatment with inhaled steroids has increased continuously. Objective:
The aim of this study was to analyze the net effect of these changes i
n terms of hospitalization of children for treatment of asthma. Method
s: The numbers of hospital days, admissions, and individual patients a
dmitted to the Children's Hospital in Goteborg because of acute asthma
were recorded from 1985 through 1993. All the in-patient treatment of
children is centralized at this hospital (i.e., the study was populat
ion-based). Goteborg has half a million inhabitants. Hospitalization p
olicies were not altered during the study period. Results: In children
aged 2 to 18 years, the number of hospital days per year gradually de
creased to less than a third (r = 0.9; p < 0.001), and admissions decr
eased by 45% (r = 0.7; p < 0.05). The decrease in hospitalization was
most marked in the group older than the age of 5 years in which hospit
al days were reduced to one fifth (r = 0.9; p < 0.0001) and admissions
were halved (r = 0.8; p < 0.05). A decreasing trend in number of hosp
ital days was also seen in the 2- to 5-year-old group. The number of i
ndividual patients admitted did not show a statistically significant d
ecreasing trend. In children under the age of 2 years, the number of h
ospital days fluctuated, and there was no clear-cut change with time.
Conclusion: Although increased concentration on the education of paten
ts and patients may have been a contributing factor, the major reason
for the decrease in hospitalization in the group of children aged 2 to
18 years is most probably antiinflammatory treatment with inhaled ste
roids. The results suggest that this is a very cost-effective therapeu
tic approach.