Jr. Kosko et Cs. Derkay, ROLE OF CESAREAN-SECTION IN PREVENTION OF RECURRENT RESPIRATORY PAPILLOMATOSIS - IS THERE ONE, International journal of pediatric otorhinolaryngology, 35(1), 1996, pp. 31-38
Recurrent respiratory papillomatosis (RRP) is a benign yet aggressive
neoplasm that produces considerable morbidity in children. Previous st
udies have linked RRP in children to mothers with genital tract human
papillomavirus infections (HPV), Risk factors for vertical transmissio
n have not been well identified. Controversy exists among obstetrician
s and otolaryngologists regarding the role of cesarean section in prev
enting the transmission of HPV disease from mother to child. We addres
s this issue by presenting the results of a national survey of otolary
ngologists, the American College of Obstetrics and Gynecology position
statement, the relevant literature regarding the association between
RRP and maternal HPV, and the proposed mechanisms for HPV transmission
at birth. We postulate a very limited role for cesarean section in pr
eventing transmission of RRP, given our present knowledge of this dise
ase.