ASYMMETRIC-SYNTHESIS OF SUBSTITUTED FUNCTIONALIZED CIS AND TRANS VINYLCYCLOPROPANES VIA PALLADIUM-CATALYZED REACTIONS

Authors
MICHELET V BESNIER I GENET JP
Citation
V. Michelet et al., ASYMMETRIC-SYNTHESIS OF SUBSTITUTED FUNCTIONALIZED CIS AND TRANS VINYLCYCLOPROPANES VIA PALLADIUM-CATALYZED REACTIONS, Synlett, (3), 1996, pp. 215
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
3
Year of publication
1996
Database
ISI
SICI code
0936-5214(1996):3<215:AOSFCA>2.0.ZU;2-O
Abstract
A facile method for synthesizing irons and cis disubstituted vinylic c yclopropanes is described. The key steps are alkylation of chiral ally lic alcohols and cyclisation via SN Of functionalized allylic substrat es using palladium (0) catalyst with high regio- and stereoselectivity .