The six major ginsenosides, Rg(1), Re, Rb-1, Re, Rb-2, and Rd, in root
s and leaves of American ginseng have been isolated and quantified by
high-performance liquid chromatography. In 4-year-old roots, the main
ginsenosides were Re and Rb-1, and together they accounted for >75% of
the total ginsenosides. In leaves, the concentration and composition
of ginsenosides varied with the maturity of the leaf tissue. One-month
-old leaves contained 1.33-2.64 g ginsenoside/100 g dry weight, and th
e ginsenoside Re accounted for >50% of the total concentration. In mat
ure, 4-month-old leaves, the total ginsenoside content ranged from 4.1
4 to 5.58 g/100 g dry weight, and the ginsenosides Re and Rd each acco
unted for similar to 40% of the total ginsenosides. The production sit
e of ginseng influenced the ginsenoside contents of roots and leaves.
However, few significant correlations were found between root and leaf
ginsenosides and between ginsenoside levels and mineral composition o
f the leaves and soil.