SUBSTITUTED 2-ALKOXY-5-AMINO-IMIDAZOLE AN D 2-ALKOXY-2,5-DIAMINO-IMIDAZOLE FROM OXAZOL-2-YLIDEN-CYANAMIDES

Authors
GEWALD K ANGERMANN J SCHAFER H
Citation
K. Gewald et al., SUBSTITUTED 2-ALKOXY-5-AMINO-IMIDAZOLE AN D 2-ALKOXY-2,5-DIAMINO-IMIDAZOLE FROM OXAZOL-2-YLIDEN-CYANAMIDES, Monatshefte fuer Chemie, 127(3), 1996, pp. 313-318
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
127
Issue
3
Year of publication
1996
Pages
313 - 318
Database
ISI
SICI code
0026-9247(1996)127:3<313:S2AD2>2.0.ZU;2-6
Abstract
N-Cyano-S-methyl-isothio-ureases (1) react with alpha-halogen ketones (2) by ring closure yielding the (3H-oxazol-2-yliden)-cyanamides 3. by ring transformation, -Alkoxy-5-amino-1-phenyl-3H-imidazol-4-yl)-keton es (4) are formed. Primary and secondary amines react with 3 to give 2 -N-alkylated (2,5-Diamino-1-phenyl-3H-imidazol-4-yl)-ketones.