The steady increase in the incidence of Enterobacter septicemia and th
e rapid acquisition by this organism of beta-lactam resistance pose ma
jor therapeutic challenges, Enterobacter septicemia is often nosocomia
l, At least one other organism is also present in 18% to 50% of cases,
The lead point is often a respiratory or venous focus, Most cases occ
ur in patients with critical conditions treated in intensive care unit
s. Beta-lactamase-producing strains are becoming increasingly common (
as a result of induction or derepression. Antimicrobials should be sel
ected based on stability to beta-lactamases.