Transverse myelitis and optic neuritis may be acute, self-limiting dis
orders or may be the presenting manifestations of multiple sclerosis.
The occurrence of transverse myelitis demands an investigation to excl
ude an expanding or compressive spinal cord lesion. Infectious and inf
lammatory processes must be excluded in patients with optic neuritis.
When transverse myelitis and optic neuritis occur together, this is ca
lled neuromyelitis optica, or Devic's syndrome. Neuromyelitis optica i
s rare in childhood, as is each disorder occurring alone. A literature
review in 1985 by Whitham and Brey revealed over 300 cases in all age
s (although only 80 are in the English language literature) and none y
ounger than 6 years of age.(1) We report a 4-year-old boy with neuromy
elitis optica who presented with transverse myelitis and subsequently
developed optic neuritis. The sequential magnetic resonance imaging (M
RI) findings are described, and the differential diagnosis discussed.