MANAGEMENT OF PEUTZ-JEGHERS SYNDROME - EXPERIENCE WITH PATIENTS FROM THE DANISH POLYPOSIS REGISTER

Danish patients with Peutz-Jeghers syndrome are registered in the Dani sh Polyposis Register. We have initiated a new follow-up programme bas ed on recent literature including our own cases. This has been adjuste d to the regrowth rate of the polyps whereby patients with no symptoms and low regrowth rate are followed with few examinations. The program me includes upper and lower gastrointestinal endoscopy, small bowel en ema and in cases with large or symptomatic polyps, laparotomy with int raoperative total enteroscopy with polypectomy as required. Pelvic exa mination, cervical smear, breast and testicular examination are carrie d out after the age of 30 years.